Firdaus Khan
1. When it is applied directly on a wound surface or via a dressing, it can act as a sealant, keeping the wound moist and free from contamination.
2. In addition, honey is comprised of glucose (35%), fructose (40%), sucrose (5%), and water (20%). This high sugar content plus vitamins, minerals, and amino acids) provides topical nutrition that is thought to promote healing and tissue growth.
3. Honey is also a hyperosmotic agent that draws fluid from the wound bed and underlying circulation, which kills bacteria that cannot thrive in such an environment.
4. It is bactericidal in other ways as well. During the process of honey production, worker bees add the enzyme glucose oxidase to the nectar. When honey is applied to the wound, this enzyme comes into contact with oxygen in the air, which leads to the production of the bactericide hydrogen peroxide.
5. Macroscopically, honey has also shown debriding action.
6. Manuka (Medihoney) is a medicinal honey with enhanced antibacterial properties derived from floral sources in Australia and New Zealand Canada
7. Peter Molan, a New Zealand biochemist at the University of Waikato
8. Research at the University of Sydney
9. About 17 randomized controlled trials involving a total of 1965 participants have been published; 5 other types of clinical trials involving 97 participants treated with honey have also been reported in the literature. Furthermore there are about 16 trials of honey on a total of 533 wounds in animal models (which rule out a placebo effect). There are over 270 cases, of mostly chronic wounds cited in the literature that were treated with honey. Honey gave good results in all but 14 of these cases.
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